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What Is Bioperine and What Are the Benefits


BioPerine®: The best companion for your supplements


Trying to have a healthy life can be difficult, especially when you are not getting the results you were expecting from consuming nutrient supplements.

But why’s that? That frustration might be a consequence of a bad absorption of the nutrients. Luckily, there is a compound that could improve this situation: BioPerine.

If you haven’t heard about BioPerine before you might now be curious about what it can do for you. Here we will show you everything you need to know about BioPerine.

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“BioPerine is a patented extract obtained from black pepper fruits” -FormulateHealth (BioPerine - What Is It and What Does It Do? (

It was researched and created by the company Sabinsa in 1988. BioPerine is mainly composed of piperine, which is the bioactive ingredient in black pepper, and it is also what gives black pepper the spicy flavor. 

Is it different from Black pepper?

Piperine can be naturally obtained from the black pepper, and it’s possible to increment its levels in your diet by increasing the amount of black pepper you consume, but it can´t be compared with the levels present in BioPerine.

“The bioavailability of piperine in black pepper alone isn’t as high as it is in BioPerine, which contains a minimum of 95 percent if piperine” -Formulate Health (BioPerine - What Is It and What Does It Do? ( 

This limitation in the availability of piperine in black pepper is no longer a problem with BioPerine as it is an extract that maximizes the contents of the bioactive compound.

What are BioPerine benefits?

As mentioned before, piperine is the bioactive ingredient in black pepper. This means it interacts inside your body and has a biological effect when consumed. 

Its beneficial physiological effects have been known for ages, but it’s just now, with access to high technology, that we can know more of these benefits and even discover new ones. 

Nutrient Absorption

This one is the benefit BioPerine is famous for. It has been found that BioPerine can boost the absorption of nutrients through an ability called “bioenhancement”

“This means you get more out of other nutrients that you consume” -Neurohacker (6 Impactful Benefits of Bioperine and Piperine Supplements (

That’s why this ingredient is often used in supplements.

Anti-inflammatory and antiarthritic effects

The anti-inflammatory effects might not be as well-known as the other ones on this list. However, it shows the great potential of the piperine on health improvement.

Lately, scientists (Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models ( have discovered that piperine extract reduces pain and arthritic symptoms, and it also decreases the inflammatory area in the ankle joints.

Protects your mental health

The beneficial properties of piperine don’t end on enhance how you look and how your body functions, in fact, it can also protect your mental health. 

Studies (Anxiolytic and antidepressant profile of the methanolic extract of Piper nigrum fruits in beta-amyloid (1–42) rat model of Alzheimer’s disease ( have shown that the administration of Black pepper extract causes anxiolytic and antidepressant-like effects.

This application could be exploded in a bigger extent for future treatment.

That’s not it. The piperine combined with curcumin potentiates curcumin’s capacity to boost serotonin and dopamine levels, as proved by Kumar (Anxiolytic and antidepressant profile of the methanolic extract of Piper nigrum fruits in beta-amyloid (1–42) rat model of Alzheimer’s disease (

Depression and anxiety treatments are not the only ones related to piperine. Another research from 2017 (Anticonvulsant effect of piperine ameliorates memory impairment, inflammation and oxidative stress in a rat model of pilocarpine-induced epilepsy ( shows that piperine has anticonvulsant effects that ameliorate memory impairment, inflammation and oxidative stress in epilepsy models. 

Weight loss

Staying healthy it’s important, but when a product can do both taking care of you and making you look fit, it’s just a super win.

“Piperine protects against obesity and improves lipid metabolism” – Du Yafang (Effects of piperine on lipid metabolism in high-fat diet induced obese mice - ScienceDirect) 

This research pointed out the fact that piperine also has effects on weight loss in the studied model.

Improves the Immune system

When the Immune system is going through some difficulties it could produce aggressive responses, even with the most insignificant stimuli.

This is a negative thing, and it needs to be controlled. Fortunately, investigations (Piperine inhibits cytokine production by human peripheral blood mononuclear cells - PubMed ( have discovered that piperine has a regulating effect on the immune system cells that could help to treat that issue. 

This means that thermogenesis determines the rate at which the body absorbs the nutrients.

“The BioPerine increases the term energy sufficient to “power up” the mechanism related to thermogenesis” -Becarre (Focus on Bioperine, the nutrient absorption enhancer (

BioPerine achieves a greater nutrient absorption by making the body need more nutrients for thermogenesis, therefore it must take more out of the food it processes in the gut.  

Does it have contraindications?  

As every compound new in our diet, we should be aware of the special precautions and warnings. 

In the case of BioPerine, there is almost no side effects when it is consumed at the recommended dosage. 

However, If you are currently taking medicine you should consult with your doctor if the piperine could interact in a negative way with your medication. 

What is the recommended dosage? 

To prevent any discomfort, it’s necessary to follow the recommended dosage of BioPerine. These recommendations allow us to take advantage of the benefits that piperine offers to you.

According to Becarre (Focus on Bioperine, the nutrient absorption enhancer (, the recommended dosage is 5 mg per serving dose. 

This amount of piperine is almost 4000 times lower than the toxic dosage in tested models.

This amount of piperine is almost 4000 times lower than the toxic dosage in tested models.

Black Pepper Supplement — Health Benefits, Dosage, Side Effects |

How is it consumed?

The recommended dosage seems extremely low and could appear to be difficult to control, then how is BioPerine consumed?

BioPerine is unlikely consumed alone, instead it is commonly added to curcumin supplements since curcumin has a low bioavailability and absorption rate. 

It can also be added to another nutrient supplements.

The products that contain piperine already take in consideration the recommended dosage, so there’s no need for you to calculate how much piperine you must ingest. You just have to worry about following the instructions on your product.

Why do turmeric and BioPerine are such a great dynamic duo?

Turmeric and its bioactive compound, curcumin, have been largely studied because of its potential to treat various health conditions. 

Scientific research supports its use because of the benefits it provides.

However, the greatness of the curcumin crashes against an enemy: low absorption.

“The curcumin inIt has been established that BioPerine enhances the absorption of the nutrients and therefore boosts their benefits. turmeric is poorly absorbed into the bloodstream” -Healthline (Why Turmeric and Black Pepper Is a Powerful Combination (

Happily, BioPerine has become the perfect partner for turmeric supplements because of its absorption boosting properties.

Where to buy products with BioPerine

It has been established that BioPerine enhances the absorption of the nutrients and therefore boosts their benefits. 

Some of the products offered by Mother Nature Organics contain this special ingredient that highlights their properties.


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